Studies on Xanthine Oxidase. VI
نویسندگان
چکیده
منابع مشابه
Xanthine Oxidase. Vi. Influence of Ph on Substrate Specificity.
Milk xanthine oxidase exhibits a broad substrate specificity that includes purines, aldehydes, and pteridines (1). The mechanism of substrate oxidation, particularly that of purines, has been the subject of several studies (2-4). The present report concerns the observation of a new class of substrates, quaternary heterocyclic compounds, which are oxidized at pH values above 9.6. A partial list ...
متن کاملXanthine Oxidase VI. INFLUENCE OF pH ON SUBSTRATE SPEClFICITY*
Milk xanthine oxidase exhibits a broad substrate specificity that includes purines, aldehydes, and pteridines (1). The mechanism of substrate oxidation, particularly that of purines, has been the subject of several studies (2-4). The present report concerns the observation of a new class of substrates, quaternary heterocyclic compounds, which are oxidized at pH values above 9.6. A partial list ...
متن کاملFurther studies with xanthine oxidase inhibitors.
The osidase and dehydrogenase activities in the enzymes oxidizing xanthine can be differentiated by the use of certain inhibitors (1). The present study was designed to see if such inhibitors are specific for the reaction with oxygen, or whether these agents also block the transfer of electrons to cytochrome c and nitrate. Both reduced diphosphopyridine nucleotide and hypoxanthine were studied ...
متن کاملRecent mechanistic studies of xanthine oxidase.
Introduction The molybdenum-containing hydroxylases constitute one of the three major categories of mononuclear molybdenum enzymes. In comparison with other biological hydroxylation systems they are unique in that they utilize water rather than dioxygen as the ultimate source of the oxygen atom incorporated into product, and generate rather than consume reducing equivalents in the course of tur...
متن کاملRecent studies on xanthine oxidase and related enzymes.
Chemistry and Biochemistry of Flavoenzymes (Muller, F., ed.), vol. 111, pp. 309-317, CRC Press, Boca Raton 7 Ratti, S., Curti, B., Zanetti, G. and Galli, E. (1985) J. Bacteriol. 163, 724-729 8 Vanoni, M. A., Negri, A., Zanetti, G., Ronchi, S. and Curti, B. (1990) Biochem. Biophys. Acta 1039, 374-377 9 Vanoni, M. A., Nuzzi, L., Rescigno, M., Zanetti, G. and Curti, B. (1991) Eur. J. Biochem. 202,...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1925
ISSN: 0306-3283
DOI: 10.1042/bj0190672